Protein name:
SUMO-conjugating enzyme UBC9 ;
Alternative:
Ubiquitin carrier protein 9 ;SUMO-protein ligase ;Ubiquitin-conjugating enzyme E2 I ;Ubiquitin carrier protein I ;Ubiquitin-protein ligase I ;Ubiquitin-conjugating enzyme UbcE2A ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1, PARP, HIPK1, HIPK2 and PPM1J. Interacts with various transcription factors such as TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4. Interacts with RWDD3; the interaction enhances the sumoylation of a number of proteins such as HIF1A and I-kappa-B Interacts with FOXL. Forms a complex with SENP6 and UBE2I in response to UV irradiation. Interacts with DNM1l; the interaction Interacts with DNM1l (via its GTPase and B domains); the interaction promotes sumoylation of DNM1L, mainly in its B domain. Interacts with NFATC2IP; this inhibits formation of poly-SUMO chains (By similarity). Interacts with RASD2 AND TCF3.
Function:
Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5.
Subcellular Location:
Nucleus
Cytoplasm
Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.
Protein Attributes:
50:
MSGIALSRLA | QERKAWRKDH | PFGFVAVPTK | NPDGTMNLMN | WECAIPGKKG |
100:
TPWEGGLFKL | RMLFKDDYPS | SPPKCKFEPP | LFHPNVYPSG | TVCLSILEED |
150:
KDWRPAITIK | QILLGIQELL | NEPNIQDPAQ | AEAYTIYCQN | RVEYEKRVRA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Human
Mouse
Rat
ELISA Kit for Rat SUMO-conjugating enzyme UBC9
ELISA Kit for Rat SUMO-conjugating enzyme UBC9
ELISA Kit for Rat SUMO-conjugating enzyme UBC9
ELISA Kit for Rat SUMO-conjugating enzyme UBC9
CLIA Kit for Rat SUMO-conjugating enzyme UBC9
CLIA Kit for Rat SUMO-conjugating enzyme UBC9
CLIA Kit for Rat SUMO-conjugating enzyme UBC9
CLIA Kit for Rat SUMO-conjugating enzyme UBC9
Polyclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Polyclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Polyclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Polyclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Monoclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Monoclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Monoclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Monoclonal Antibody for Rat SUMO-conjugating enzyme UBC9
Protein for Rat SUMO-conjugating enzyme UBC9
Protein for Rat SUMO-conjugating enzyme UBC9
Protein for Rat SUMO-conjugating enzyme UBC9
Protein for Rat SUMO-conjugating enzyme UBC9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH TCF3;SUBCELLULAR LOCATION
strain :
CD Charles River .
tissue :
Aorta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Ovary .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RASD2